CD10 is a cell surface enzyme with neutral metalloendopeptidase activity. CD10 is also known as CALLA (common acute lymphocytic leukemia antigen). It serves as a marker for the common form of ALL (acute lymphocytic leukemia) as well as for Burkitt lymphoma and follicular germinal center lymphoma. CD10/CALLA is normally present on the surface of early lymphoid cells as well as on a number of other types of normal cells, such as especially cells in the kidney.
Abbkine CD10 Monoclonal Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific peptide to detect endogenous CD10 proteins. The antibody has been validated for IHC-P, IF and tested in Human, Mouse and Rat. Supplied in liquid solution, the concentration of the antibody is 1mg/ml. The antibody is for research use only.
To validate the staining in rat kidney tissue sections, we chose Abbkine CD10 Monoclonal Antibody as the primary antibody. A goat polyclonal to mouse IgG1 was used as the secondary antibody. A positive result was found and no non-specific background. Negative control was used by secondary antibody only. I was happy with the result. I found it to be worth the cost and plan to use them again.