Abbkine Scientific Company Limited is one of the very popular scientific solutions providers, with numerous tools, antibodies, resins and other such products coming from them. Therefore, it did not come as a surprise to many when it recently announced the release of its new monoclonal antibody – CD21 Monoclonal Antibody, otherwise known as the CD21 antibody.
Like most of the other antibodies and resins, the Complement receptor type 2 antibody has come different reviews from experts and other such stakeholders in the industry.
What is CD21 Monoclonal Antibody?
CD21 Monoclonal Antibody also known as the C3DR antibody, the antibody is a somewhat unique antibody with amazing features that has endeared it to many researchers and investigators across the globe.
CR2 encodes a membrane protein known as complement C3d receptor 2. The membrane protein is reputed to function as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. In addition to this feature, the genetic variations in CR2 are susceptible to systemic lupus erythematosus type 9 also known as SLEB9. Alternatively, spliced transcript variants encoding different isoforms have been found for CR2.
Features of CD21 Monoclonal Antibody
The antibody comes with different features and benefits, some of which are briefly highlighted below
- Immunogen – Synthetic Peptide
- Host – Mouse
- Reactivity – mouse, human, and rat
- Applications – IF and IHC-p
- Clonality – monoclonal
- Isotype – Mouse IgG1
- Formulation – Liquid solution
- Concentration – 1 mg/ml
- Gene ID – 1380
- Storage buffer – PBS pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol
CD21 Monoclonal Antibody – Pros
The features of the monoclonal antibody mentioned above have clearly showed some of the perceived benefits of pros of the product, especially when compared to others in the market.
One of such pros is the formulation of the antibody. As a liquid formulation, the antibody can be easily applied by researchers and investigators.
The purification process of the antibody also distinguishes it from its peers. The antibody was affinity-purified from mouse ascites by affinity chromatography using specific immunogen.
The storage buffer of PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol is also one of the pros of the product.
The antibody also detects endogenous CD21 proteins, another of its relatively many desirable features.
The CD21 Monoclonal antibody by Abbkine Scientific can be stored for as long as one year at -20°C from the date of shipment. The ease of storage and durability ensure that users can hold onto it for a long period.
There is also flexibility in its use as investigators can determine the optimal working dilutions by experiments, even as the suggested starting dilutions are IHC-p: 1:200, IF: 1:200.
CD21 Monoclonal Antibody – Cons
So far, there are no cons readily identified for the antibody. However, continuous of the use of the product by researchers and investigators alike would reveal possible drawbacks.
CD21 Monoclonal Antibody – Final Verdict
After a comprehensive assessment of the CD21 Monoclonal Antibody, one can confidently say that researchers and investigators have a reliable antibody to work with.