EPAS-1 Polyclonal Antibody Review

Endothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2alpha)) is a protein that in humans is encoded by the EPAS1 gene. It is a type of hypoxia-inducible factor, a group of transcription factors involved in body response to oxygen level. The gene is active under low oxygen condition called hypoxia. It is also important in the development of the heart, and maintaining catecholamine balance required for protection of the heart. Mutation often leads to neuroendocrine tumors. However, a special version (allele) of EPAS1 produces EPAS1 which is responsible for high-altitude adaptation in humans. It is known that the variant gene confers increased athletic performance in some people, and hence it is dubbed the “super athlete gene”.

EPAS-1 Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been tested with WB, IHC-p and ELISA. And Abbkine suggested starting dilutions are as follows:  WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000.

EPAS 1 is involved in the development of the embryonic heart and is expressed in the endothelial cells that line the walls of the blood vessels in the umbilical cord. Responsible to say, EPAS-1 Polyclonal Antibody is a very good product. It works well. And this product is what I want.

 

EPAS-1 Polyclonal Antibody
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$100

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Review Summary:

EPAS 1 is involved in the development of the embryonic heart and is expressed in the endothelial cells that line the walls of the blood vessels in the umbilical cord. Responsible to say, EPAS-1 Polyclonal Antibody is a very good product. It works well. And this product is what I want.

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