The HSP70 monoclonal antibody is a unique antibody from popular scientific research company, Abbkine Scientific Company Limited. The research outfit headquartered in China has launched different research products including antibodies and the HSP70 Monoclonal Antibody is another amazing scientific discovery, made to help research scientist carry out their task easier and more effectively.
The product otherwise known as HSPA1 Antibody is unique due to its features and inherent benefits, especially when compared to other products of similar nature. The HSPA1L encodes a 70kDa heat shock protein, a distinct attribute of the product. This is in addition to encoding other heat shock proteins and heat shock protein family A (Hsp70) member 1, helping to stabilize existing proteins against aggregation and also mediating the folding of proteins that are newly translated in the cytosol and in organelles.
HSPA1L is found in the main histocompatibility complex class III region, located in a cluster with two different but closely related genes that also encode isoforms of the 70kDa heat shock protein.
Features of the HSP70 Monoclonal Antibody
The product comes with different features that do not only distinguish from the competition, but make it one of the most sought-after monoclonal antibody in the science research world. Some of these features are listed below.
. The HSP70 is formulated in a liquid solution, ensuring ease of use by science researchers and other such users.
. The product has a 1 mg/ml concentration, making it one of the best in the market.
. The storage buffer is PBS, pH 7.4, containing 0.02% sodium oxide as Preservative and 50% Glycerol, helping to maintain its efficiency.
. The HSP70’s immunogen is synthetic peptide.
. The product has a relatively long life span if stored under recommended conditions. The storage instruction of the HSP70 states that the product can be stable for as much as a year at a temperature of -20°C from the shipment date.
. The HSP70 is easy to recover from storage, with a recommended method of centrifuging the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
. The mouse is the host and the HSP70 reacts with rat, mouse and human.
. Its applications are IF and WB, with a recommended starting dilution of between 1:1000 and 2000 for WB, and 1:100 and 200 or IF. The investigator is however advised to determine the optimal working dilutions through experiments.
. It is monoclonal with Mouse IgG1 isotype.
Pros and Cons of the HSP70
There has been no reported case of cons, defects or unsatisfactory remarks about the antibody. This however does not take away the fact that such situations might arise as time passes, but with the continuous effort of the team at Abbkine, defects are expected to be corrected almost immediately they are spotted.
One of the pros of the HSP70 is its purification, as it was affinity-purified from mouse ascites using specific immunogen to guarantee its safety.
Its relatively long lifespan is another merit of the HSP70 as it can last for as long as one year after the shipment date if stored under proper conditions stated above.
The effective detection of endogenous HSP70 proteins is another advantage of the HSP70.
Abbkine have warned against using the product for clinical or human diagnosis as it was specifically made for research use. The HSP70 monoclonal antibody is one that would greatly benefit the science world and researchers in particular, thanks to its amazing features and benefits.