p53 (Acetyl Lys382) Polyclonal Antibody Review

p53 (Acetyl Lys382) Polyclonal Antibody ReviewThe p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis . Acetylation appears to play a positive role in the accumulation of p53 protein in stress response . Following DNA damage, human p53 becomes acetylated at Lys382 (Lys379 in mouse) in vivo to enhance p53-DNA binding.

Abbkine p53 (Acetyl Lys382) Polyclonal Antibody are produced by immunizing Rabbits with a synthetic acetylated peptide corresponding to residues surrounding Lys382 of human p53. The antibody detects endogenous levels of human p53 only when acetylated at lysine 382 and suitable for WB, IHC-p, ELISA.

Abbkine p53 (Acetyl Lys382) Polyclonal Antibody is used to stain human breast adenocarcinoma formalin fixed paraffin embedded tissue sections, 10μg/ml working concentration, for 15 mins at room temperature and detected using an HRP conjugated secondary antibody. The target staining is very clear and the sensitivity of the antibody was  perfect.

p53 (Acetyl Lys382) Polyclonal Antibody Review
  • Editor Rating

  • Rated 4.5 stars
  • Outstanding
$100

  • Product Features
    Editor: 95%
  • Usage Performance
    Editor: 95%
  • Price Advantage
    Editor: 95%

Review Summary:

Abbkine p53 (Acetyl Lys382) Polyclonal Antibody is used to stain human breast adenocarcinoma formalin fixed paraffin embedded tissue sections, 10μg/ml working concentration, for 15 mins at room temperature and detected using an HRP conjugated secondary antibody. The target staining is very clear and the sensitivity of the antibody was perfect.

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