PCNA and Cell Proliferation

Proliferating cell nuclear antigen (PCNA) protein is one of the central molecules responsible for decisions of life and death of the cell, and it is an important cell proliferation marker. In addition, the evaluation of cell proliferation activity in tumors provides useful information for assessing diagnosis, clinical behavior, and therapy in latest research flow.

 

PCNA was originally identified as an antigen that is expressed in the nuclei of cells during the DNA synthesis phase of the cell cycle. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.

 

PCNA, Proliferating cell nuclear antigen

Picture Source: Journal of Cell Science (Powered by The Company of Biologists)

 

Abbkine recently launched a series of primary antibody with full validation to help scientist’s research, in which I highly recommend PCNA Polyclonal Antibody, you can refer to the specific product information in below chart:

 

Product Name Catalogue Number Reactivity Application Concentration Size and Price
PCNA Polyclonal Antibody ABP0112 Human, Monkey, Mouse, Rat ELISA, IHC-p, WB 1 mg/ml $280/100μl
(Up to 50% discount extra)

 

For quality assurance, you can also see below validation result provided by Abbkine factory:

 

 ABP0112-1 Fig.1. Western Blot analysis of various cells using PCNA Polyclonal Antibody diluted at 1:2000
  Fig.2. Western Blot analysis of COS7 cells using PCNA Polyclonal Antibody diluted at 1:2000.

 

Further, there are many other products that Abbkine provides to help you study PCNA. I selected some hot products for you and listed as below:

 

Catalogue Number Product Name
A01040 Anti-PCNA Mouse Monoclonal Antibody (1D7) – 6 publications, quality choice
A01040A488 Anti-PCNA Mouse Monoclonal Antibody (1D7), AbFluor™ 488 Conjugated – Direct conjugation
KTE62481 Human Proliferating cell nuclear antigen antibody (PCNA) ELISA Kit – $450/96tests
BMM3001 Colorcode Prestained Protein Marker (10-180 kDa) – Common item for Western Blot

 

If you are interested in any of items that Abbkine provides to study PCNA, feel free to contact Abbkine service representative at service@abbkine.com, you will get reply shortly.

 

About Abbkine Scientific Co., Ltd.

Abbkine offers services for global scientists in the fields of proteomics and cytology, and is committed to the innovation and development of various scientific reagents related to proteomics and cytology, to promote the development of fields including life science research and drug discovery. Proteomics products cover the preparation of samples (protein extraction, purification, coupling), protein quantification, antibodies and kits for protein detection. Cytology products involve cytokines (cell culture), cell status detection, cell staining, organelle extraction, cell metabolism and cytopathology reagents (kits). Abbkine relies on the product portfolio and unique marketing support as the main market strategy and product innovation mode, to help your research career!

 

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