Tumor Necrosis Factor Alpha, Inflammation and Influenza Virus

Tumor Necrosis Factor Alpha(TNF-α) is a cytokine that refers to systemic inflammatory response syndrome(SIRS), at the same time, it is also one of cytokines which bring acute phase reaction. It is majorly secreted by macrophage, but other types of cells can produce Tumor Necrosis Factor Alpha as well. Surprisingly scientists found that Tumor Necrosis Factor Alpha can inhibit the duplication of different kinds of influenza virus, having strong anti-virus capacity.

 

Tumor Necrosis Factor Alpha inhibitor can provide reference for many inflammation diseases, such as rheumatoid arthritis, spondyloarthritis, psoriasis and inflammatory bowel disease. Compared with other traditional unspecific immunological inhibitor to treat systemic inflammatory response syndrome(SIRS), Tumor Necrosis Factor Alpha inhibitor provides a fresh new targeted therapy strategy. However the use of Tumor Necrosis Factor Alpha inhibitor may bring other side affects to the patient being treated including below:

◎Headache and Inflammation

◎Increased serum alanine aminotransferase (ALT)

◎Abdominal pain, nausea and diarrhea

◎sinusitis, cough and pharyngitis

◎Anemia

◎Skin rash

◎Injection site reactions

Figure 1: Tumor Necrosis Factor inhibitor side effects

(Picture Source: https://healthjade.net/tumor-necrosis-factor/)

Through year’s of efforts, Abbkine scientists have developed our own antibodies and ELISA Kits which helps the study of Tumor Necrosis Factor Alpha on experimental level. Here I listed part of them as below for your kind reference.

 

Antibody:

Product Name Catalogue Number Application Reactivity
TNF-α Polyclonal Antibody

 

ABP0127 ELISA, IF, IHC-p, WB Human, Mouse, Rat
TNF-α Polyclonal Antibody

 

ABP52882 ELISA, IHC-p, WB Human

 

ELISA Kit:

Product Name Catalogue Number Size Price
EliKine™ Human TNF-α ELISA Kit

 

KET6032 48T/96T $140/$220
EliKine™ Mouse TNF-α ELISA Kit KET7015 48T/96T $140/$220
EliKine™ Rat TNF-α ELISA Kit

 

KET9007 48T/96T $140/$220

 

Affiliate Products:

Product Name Catalogue Number Size Price
ExKine™ Nuclear and Cytoplasmic Protein Extraction Kit

 

KTP3001 50T/200T $90/$220
Protease Inhibitor Cocktail (100X)

 

BMP1001 1ml/1mlx5 $40/$120
Protein Quantification Kit (BCA Assay)

 

KTD3001 500T/2000T $45/$100
Colorcode Prestained Protein Marker (10-180 kDa)

 

BMM3001 100ul/250ulx2 $20/$62

 

Accumulating research evidence indicates that many patients seriously affected by COVID-19 might have a cytokine storm syndrome.This suggests that people with serious COVID-19 or suspected COVID-19 infection, should be monitored for hyperinflammation. Tumor Necrosis Factor Alpha(TNF-α) has close relation with inflation and Influenza virus.

 

If you are interested in study any of cytokines, Abbkine can provide you related products accordingly. The sample pack is available for trail use, feel free to contact us to get it for your experiment! Wait you at service@abbkine.com ! Email us!

About Abbkine Scientific Co., Ltd.

Abbkine offers services for global scientists in the fields of proteomics and cytology, and is committed to the innovation and development of various scientific reagents related to proteomics and cytology, to promote the development of fields including life science research and drug discovery. Proteomics products cover the preparation of samples (protein extraction, purification, coupling), protein quantification, antibodies and kits for protein detection. Cytology products involve cytokines (cell culture), cell status detection, cell staining, organelle extraction, cell metabolism and cytopathology reagents (kits). Abbkine relies on the product portfolio and unique marketing support as the main market strategy and product innovation mode, to help your research career!

 

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