VEGF-A shows prominent activity with vascular endothelial cells, primarily through its interactions with the VEGFR1 and -R2 receptors found in prominently on the endothelial cell membrane. Vascular endothelial growth factor A (VEGF-A) is a dimeric glycoprotein that plays a significant role in neurons and is considered to be the main, dominant inducer to the growth of blood vessels. VEGFA is essential for adults during organ remodeling and diseases that involve blood vessels, for example, in wound healing, tumor angiogenesis, diabetic retinopathy, and age-related macular degeneration. The differentiation of endothelial cells is dependent upon the expression of VEGFA and if the expression is abolished then it can result in the death of the embryo.
VEGF-A Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been tested with IHC-p and ELISA. And Abbkine suggested starting dilutions are as follows: IHC-p: 1:100-1:300, ELISA: 1:10000.
To study the expression of the vascular endothelial growth factor-A, and Protein and the ralation among the expression of the factors with cervical lymph nodes metastasis in laryngeal squamous cell carcinoma. VEGF-A gene protein in 50 cases of laryngeal carcinoma and 15cases of normal tissue around the cancer were detected by immunohistochemistry. I chose Abbkine, it never let me down.